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NR162

CAT: 0804-HY-115719-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-115719-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NR162 (compound 26) is a highly potent and selective CASK inhibitor (Kd of 22 nM) [1].
CAS Number
2755241-73-5
UNSPSC
12352005
Target
Ser/Thr Kinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cask-in-1.html
Purity
99.7
Solubility
DMSO : 12.21 mg/mL (ultrasonic; warming)
Smiles
O=C(C1=CN=C(N=C1NC2CCCC2)NCC3=CC(Br)=C(C=C3Br)C)NCCCN4CCOC4=O
Molecular Formula
C24H30Br2N6O3
Molecular Weight
610.34
References & Citations
[1]Russ N, et al. Design and Development of a Chemical Probe for Pseudokinase Ca2+/calmodulin-Dependent Ser/Thr Kinase. J Med Chem. 2021 Oct 14;64 (19) :14358-14376.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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