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Piprofurol

CAT: 0804-HY-114920Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-114920Size:1 Each
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Description
Piprofurol is a calcium channel inhibitor. Piprofurol inhibits the calcium-induced contractions in isolated potassium depolarized preparations of rat aorta in a concentration-dependent manner and relaxes the K+-induced contraction of the dog coronary artery and the rabbit basilar artery. Piprofurol exerts a negative inotropic effect on guinea-pig papillary muscle, with the EC50 of 5 μM[1].
CAS Number
40680-87-3
UNSPSC
12352005
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/piprofurol.html
Solubility
10 mM in DMSO
Smiles
OC(C1=C(C(OC)=C2OC=CC2=C1OC)OCCN3CCCCC3)CCC4=CC=C(C=C4)O
Molecular Formula
C26H33NO6
Molecular Weight
455.54
References & Citations
[1]Pourrias B, et al. Calcium blocking properties of piprofurol. Arch Int Pharmacodyn Ther. 1985;274 (2) :223-239.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
T25962-01Piprofurol

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