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Eritadenine

CAT: 0804-HY-114866Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-114866Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Eritadenine (D-Eritadenine) is a potent AdoHcyase inhibitor, with an IC50 value of 7 nM. Eritadenine is also an acyclic sugar adenosine analogue. Eritadenine exhibits an inhibitory effect on the growth of Cryptosporidium parvum, with a MIC50 of 3 μM. Eritadenine can be used in the research of colorectal adenocarcinoma[1][2].
CAS Number
23918-98-1
Product Name Alternative
Lentinacin; D-Eritadenine; Lentysine
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Nucleoside Antimetabolite/Analog; Parasite
Type
Natural Products
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
Neuroscience-Neuromodulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/eritadenine.html
Purity
97.9
Solubility
10 mM in DMSO
Smiles
O=C([C@@H]([C@@H](CN1C=NC2=C(N=CN=C12)N)O)O)O
Molecular Formula
C9H11N5O4
Molecular Weight
253.21
Precautions
H302, H315, H319, H335
References & Citations
[1]Huang Y, et al. Inhibition of S-adenosylhomocysteine hydrolase by acyclic sugar adenosine analogue D-eritadenine. Crystal structure of S-adenosylhomocysteine hydrolase complexed with D-eritadenine. J Biol Chem. 2002 Mar 1;277 (9) :7477-82. |[2]Ctrnáctá V, et al. Efficacy of S-adenosylhomocysteine hydrolase inhibitors, D-eritadenine and (S) -DHPA, against the growth of Cryptosporidium parvum in vitro. Exp Parasitol. 2010 Oct;126 (2) :113-6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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