Taprostene

• Description :

  Taprostene (CG-4203) is a synthetic, chemically stable analogue of Prostacyclin (PGI2) . Taprostene exhibits endothelium and myocardial protecting actions after acute myocardial ischemia and reperfusion in cats. Taprostene enhances cytoprotective actions, while minimizing unwanted hemodynamic effects[1].

• Product Name Alternative :

  CG-4203

• UNSPSC :

  12352005

• Target :

  Prostaglandin Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/taprostene.html

• Purity :

  98.1

• Solubility :

  10 mM in DMSO

• Smiles :

  O[C@@H](C1CCCCC1)/C=C/[C@@H]2[C@]3([H])[C@@](C[C@H]2O)([H])O/C(C3)=C\C4=CC(C(O)=O)=CC=C4

• Molecular Formula :

  C24H30O5

• Molecular Weight :

  398.49

• References & Citations :

  [1]G Johnson 3rd, et al. Endothelium and myocardial protecting actions of Taprostene, a stable prostacyclin analogue, after acute myocardial ischemia and reperfusion in cats. Circ Res. 1990 May;66 (5) :1362-70.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 3

• Isoform :

  IP

• CAS Number :

  [108945-35-3]