U27391

• Description :

  U27391 is a metalloproteinase inhibitor. U27391 inhibits rhIL-1β Induced proteoglycan loss[1].

• CAS Number :

  [106314-87-8]

• UNSPSC :

  12352005

• Target :

  MMP

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/u27391.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C([C@@H](NC([C@@H](NC(C(CC(C)C)CC(NO)=O)=O)CC(C)C)=O)CC1=CC=CC=C1)N

• Molecular Formula :

  C23H36N4O5

• Molecular Weight :

  448.56

• References & Citations :

  [1]Seed MP, et al. Inhibition of interleukin 1 beta induced rat and human cartilage degradation in vitro by the metalloproteinase inhibitor U27391. Ann Rheum Dis. 1993 Jan;52 (1) :37-43.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported