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Asobamast

CAT: 0804-HY-114538Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-114538Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Asobamast is a potent, orally active antiallergic agent that inhibits ige mediated passive pulmonary allergic responses in rats (ED50=4.7 mg/kg) and inhibits antigen-induced mediator release from sensitized guinea pig lung fragments[1].
CAS Number
104777-03-9
UNSPSC
12352005
Target
TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/asobamast.html
Solubility
10 mM in DMSO
Smiles
O=C(C(OCCOCC)=O)NC1=NC(C2=CC(C)=NO2)=CS1
Molecular Formula
C13H15N3O5S
Molecular Weight
325.34
References & Citations
[1]D Chiarino, et al. N- (4-Isoxazolylthiazol-2-yl) oxamic acid derivatives as potent orally active antianaphylactic agents. J Med Chem. 1991 Feb;34 (2) :600-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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