DL-3-Hydroxy-3-methylglutaryl coenzyme A (disodium hydrate)

DL-3-Hydroxy-3-methylglutaryl coenzyme A (disodium hydrate)

• CAS Number: 103476-21-7
• UNSPSC Description: DL-3-Hydroxy-3-methylglutaryl coenzyme A disodium hydrate is a disodium salt compound of HMG-CoA, is a intermediate of terpenes and ketone bodies. DL-3-Hydroxy-3-methylglutaryl coenzyme A disodium also involves in ester metabolism in vivo, as a precursor for cholesterol synthesis, and regulates cholesterol synthesis by coupling LDL receptor[1][2].
• Target Antigen: Biochemical Assay Reagents
• Type: Biochemical Assay Reagents
• Related Pathways: Others
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/dl-3-hydroxy-3-methylglutaryl-coenzyme-a-disodium.html
• Purity: 99.0
• Solubility: H2O : 50 mg/mL (ultrasonic;warming)
• Smiles: O[C@@H]1[C@H](OP(O)(O)=O)[C@H](O[C@H]1N2C(N=CN=C3N)=C3N=C2)COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCSC(CC(C)(O)CC(O)=O)=O)=O)=O)(O[Na])=O)(O[Na])=O.[x].O
• References & Citations: [1]Millán Núñez-Cortés J, et al. Fármacos hipolipemiantes y PCSK9 [Lipid-lowering drugs and PCSK9]. Clin Investig Arterioscler. 2016 May;28 Suppl 2:9-13. Spanish. |[2]Wang Wei, er al. The Key Enzyme of Cholesterol Synthesis Pathway:HMG CoA Reductase and Disease. PROGRESS IN PHYSIOLOGICAL SCIENCES. 1999. (01):7-11.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, sealed storage, away from moisture)
• Clinical Information: Phase 4