RID-F

• Description :

  RID-F (Ridaifen-F), a Tamoxifen (HY-13757A) derivative, is a nonpeptidic proteasome inhibitor. RID-F inhibits human 20S proteasome activity, with IC50s of 0.64, 0.34, and 0.43 μM for CT-L, T-L, and PGPH, respectively[1].

• CAS Number :

  [1020853-03-5]

• Product Name Alternative :

  Ridaifen-F

• UNSPSC :

  12352005

• Target :

  Proteasome

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/rid-f.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC/C(C1=CC=CC=C1)=C(C2=CC=C(OCCN3CCCCCC3)C=C2)\C4=CC=C(OCCN5CCCCCC5)C=C4

• Molecular Formula :

  C38H50N2O2

• Molecular Weight :

  566.82

• References & Citations :

  [1]Hasegawa M, et, al. A novel tamoxifen derivative, ridaifen-F, is a nonpeptidic small-molecule proteasome inhibitor. Eur J Med Chem. 2014 Jan:71:290-305.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported