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KY1022

CAT: 0804-HY-113680Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-113680Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KY1022 is a small molecule destabilizing Ras via targeting the Wnt/β-catenin pathway. KY1022 can inhibit cellular EMT, metastasis and apoptosis. KY1022 can be used for the research of metastatic colorectal cancer[1].
CAS Number
1029721-36-5
UNSPSC
12352005
Target
Apoptosis; Ras; Wnt; β-catenin
Type
Reference compound
Related Pathways
Apoptosis; GPCR/G Protein; MAPK/ERK Pathway; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ky1022.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(C=C1)C2=CSC3=NC=NC(NC(CC)C)=C32
Molecular Formula
C17H19N3OS
Molecular Weight
313.42
References & Citations
[1]Cho YH, et al. KY1022, a small molecule destabilizing Ras via targeting the Wnt/β-catenin pathway, inhibits development of metastatic colorectal cancer. Oncotarget. 2016 Dec 6;7 (49) :81727-81740.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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