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Debromohymenialdisine

CAT: 0804-HY-113632Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-113632Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Debromohymenialdisine (10Z-Debromohymenialdisine) is a pyrrole alkaloid. Debromohymenialdisine has moderate inhibitory activity with an IC50 value of 881 nM in the initial Raf/MEK-1/MAPK signaling cascade assay. Debromohymenialdisine can be used for the research of proliferation and differentiation[1].
CAS Number
75593-17-8
Product Name Alternative
10Z-Debromohymenialdisine
UNSPSC
12352005
Target
MEK; Raf
Type
Natural Products
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/debromohymenialdisine.html
Solubility
10 mM in DMSO
Smiles
NC(N/C1=C2CCNC(C3=C/2C=CN3)=O)=NC1=O
Molecular Formula
C11H11N5O2
Molecular Weight
245.24
References & Citations
[1]Deniz Tasdemir, et al. Aldisine alkaloids from the Philippine sponge Stylissa massa are potent inhibitors of mitogen-activated protein kinase kinase-1 (MEK-1) . J Med Chem. 2002 Jan 17;45 (2) :529-32.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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