Phytanic acid

• Description:

  Phytanic acid is an endogenous metabolite present in Blood that can be used for the research of Zellweger Syndrome, Alpha Methylacyl CoA Racemase Deficiency, Rhizomelic Chondrodysplasia Punctata and Infantile Refsum Disease[1][2][3][4][5].

• UNSPSC:

  12352211

• Hazard Statement:

  H315, H319, H335

• Target:

  Endogenous Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/phytanic-acid.html

• Concentration:

  159.98 mM * 100 μL in Ethanol

• Purity:

  99.49

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C)CCCC(C)CCCC(C)CCCC(C)CC(O)=O

• Molecular Formula:

  C20H40O2

• Molecular Weight:

  312.53

• Precautions:

  H315, H319, H335

• References & Citations:

  [1]Budden SS, et al. Dysmorphic syndrome with phytanic acid oxidase deficiency, abnormal very long chain fatty acids, and pipecolic acidemia: studies in four children. J Pediatr. 1986 Jan;108 (1) :33-9.|[2]McLean BN, et al. A new defect of peroxisomal function involving pristanic acid: a case report. J Neurol Neurosurg Psychiatry. 2002 Mar;72 (3) :396-9.|[3]Baumgartner MR, et al. Clinical approach to inherited peroxisomal disorders: a series of 27 patients. Ann Neurol. 1998 Nov;44 (5) :720-30. |[4]Poll-The BT, et al. Infantile Refsum's disease: biochemical findings suggesting multiple peroxisomal dysfunction. J Inherit Metab Dis. 1986;9 (2) :169-74.|[5]Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39 (35) :5709-5720.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Solution, -20°C, 2 years

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Human Endogenous Metabolite

• CAS Number:

  14721-66-5