cis-Urocanic acid-13C3
CAT:
804-HY-113008AS
Size:
1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
cis-Urocanic acid-13C3
- UNSPSC Description: cis-Urocanic acid-13C3 is the 13C-labeled cis-Urocanic acid. cis-Urocanic acid is a 5-HT2A receptor agonist. cis-Urocanic acid binds to 5-HT receptor with relatively high affinity (Kd=4.6 nM). cis-Urocanic acid is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor[1].
- Target Antigen: 5-HT Receptor; Isotope-Labeled Compounds
- Type: Isotope-Labeled Compounds
- Related Pathways: GPCR/G Protein;Neuronal Signaling;Others
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/cis-urocanic-acid-13c3.html
- Purity: 99.46
- Solubility: H2O : 50 mg/mL (ultrasonic;warming)
- Smiles: O=[13C](O)/[13C]=[13C]\C1=CN=CN1
- Molecular Weight: 139.09
- References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Walterscheid JP, et al. Cis-urocanic acid, a sunlight-induced immunosuppressive factor, activates immune suppression via the 5-HT2A receptor. Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17420-5.|[3]Viiri J, et al. Cis-urocanic acid suppresses UV-B-induced interleukin-6 and -8 secretion and cytotoxicity in human corneal and conjunctival epithelial cells in vitro. Mol Vis. 2009 Sep 8;15:1799-805.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, stored under nitrogen)
- Clinical Information: No Development Reported