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Inotersen

CAT: 0804-HY-112974-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-112974-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Inotersen is an antisense oligonucleotide that inhibits hepatic production of transthyretin (TTR) .
CAS Number
1492984-65-2
Product Name Alternative
GSK-2998728; ISIS-420915
UNSPSC
12352208
Target
Transthyretin (TTR)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/inotersen.html
Purity
96.44
Solubility
10 mM in H2O
Smiles
[Inotersen]
Molecular Formula
C230H318N69O121P19S19
Molecular Weight
7183.08
References & Citations
[1]Benson MD, Waddington-Cruz M, Berk JL, et al. Inotersen Treatment for Patients with Hereditary Transthyretin Amyloidosis. N Engl J Med. 2018;379 (1) :22-31.|[2]Mathew V, Wang AK. Inotersen: new promise for the treatment of hereditary transthyretin amyloidosis. Drug Des Devel Ther. 2019;13:1515-1525. Published 2019 May 6.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Oligonucleotides
Clinical Information
Launched

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