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LAU159

CAT: 0804-HY-112426Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-112426Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LAU159 is a functionally selective positive modulator of α1β3 GABA (A) receptor with an EC50 of 2.2 μM[1].
CAS Number
2055050-87-6
UNSPSC
12352005
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/lau159.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C2=CC=CC(OC)=C2)N=C3C1=CNC4=C3C=C(Cl)C=C4
Molecular Formula
C17H12ClN3O2
Molecular Weight
325.75
References & Citations
[1]Varagic Z, et al. Identification of novel positive allosteric modulators and null modulators at the GABAA receptor α+β- interface. Br J Pharmacol. 2013 May;169 (2) :371-83.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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