Revospirone

• Description :

  Revospirone (BAY Vq 7813) is a partial agonist of the 5-HT1A receptor with a Ki of 2 nmol/L. Revospirone inhibits adenylate cyclase activity with an IC50 of 124 nmol/L[1].

• CAS Number :

  [95847-87-3]

• Product Name Alternative :

  BAY Vq 7813

• UNSPSC :

  12352005

• Target :

  5-HT Receptor; Adenylate Cyclase

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/revospirone.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1C2=C(S(=O)(N1CCCN3CCN(CC3)C4=NC=CC=N4)=O)C=CC=C2

• Molecular Formula :

  C18H21N5O3S

• Molecular Weight :

  387.46

• References & Citations :

  [1]Löscher, W et al. The behavioural responses to 8-OH-DPAT, ipsapirone and the novel 5-HT1A receptor agonist Bay Vq 7813 in the pig. Naunyn-Schmiedeberg's archives of pharmacology vol. 342,3 (1990) : 271-7.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  5-HT1 Receptor