Ch55-O-C3-NH2

• UNSPSC Description:

  Ch55-O-C3-NH2 (RAR ligand 1) is a Ch 55-based ligand, which targets RAR. Ch55-O-C3-NH2 (RAR ligand 1) binds to cIAP1 ligand Bestatin via a linker to form SNIPER[1].

• Target Antigen:

  Autophagy; Ligands for Target Protein for PROTAC; RAR/RXR

• Type:

  Reference compound

• Related Pathways:

  Autophagy;Metabolic Enzyme/Protease;PROTAC;Vitamin D Related/Nuclear Receptor

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/rar-ligand-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(O)C1=CC=C(/C=C/C(C2=CC(C(C)(C)C)=CC(C(C)(C)C)=C2)=O)C=C1OCCCN

• Molecular Weight:

  437.57

• References & Citations:

  [1]Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019 Jan 25;17:160-176.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  144298-98-6