Civorebrutinib

• Description :

  Civorebrutinib (WS-413) is a Bruton's tyrosine kinase inhibitor with antineoplastic effect[1].

• CAS Number :

  [2155853-43-1]

• Product Name Alternative :

  WS-413

• UNSPSC :

  12352005

• Target :

  Btk

• Type :

  Reference compound

• Related Pathways :

  Protein Tyrosine Kinase/RTK

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/civorebrutinib.html

• Solubility :

  10 mM in DMSO

• Smiles :

  ClC(C=C1)=CN=C1OC2=CC=C(C3=NN([C@@H]4CCC5(CC5)N(C#N)C4)C(N)=C3C(N)=O)C=C2

• Molecular Formula :

  C23H22ClN7O2

• Molecular Weight :

  463.92

• References & Citations :

  [1]Wu Y, et al. 5-Aminopyrazole carboxamide derivative as BTK inhibitor and its preparation. World Intellectual Property Organization, WO2017198050 A1 2017-11-23.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported