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LJ570

CAT: 0804-HY-111775Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-111775Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LJ570 is a PPARα/PPARγ dual agonist with EC50s of 1.05 and 0.12 μM, respectively[1].
CAS Number
2252488-69-8
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/LJ570.html
Solubility
10 mM in DMSO
Smiles
OC([C@@H](OC1=CC=C(C2=CC=CC=C2)C=C1)CC3=CC=C(C4=CC=CC=C4)C=C3)=O
Molecular Formula
C27H22O3
Molecular Weight
394.46
References & Citations
[1]Laghezza A, et al. Identification of the First PPARα/γ Dual Agonist Able To Bind to Canonical and Alternative Sites of PPARγ and To Inhibit Its Cdk5-Mediated Phosphorylation. J Med Chem. 2018 Sep 27;61 (18) :8282-8298.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PPARα; PPARγ