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GSK345931A

CAT: 0804-HY-111258Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-111258Size:1 Each
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Description
GSK345931A is an EP1 receptor antagonist. GSK345931A shows measurable CNS penetration in the mouse and rat and potent analgesic efficacy in acute and sub-chronic models of inflammatory pain[1].
CAS Number
869499-38-7
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gsk345931a.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=CC(C2=C(C3=C(OCC(C)C)C=CC(Cl)=C3)C=CC=C2)=N1)O[Na]
Molecular Formula
C22H19ClNNaO3
Molecular Weight
403.83
References & Citations
[1]Hall A, et al. Discovery of GSK345931A: An EP (1) receptor antagonist with efficacy in preclinical models of inflammatory pain. Bioorg Med Chem Lett. 2009 Jan 15;19 (2) :497-501.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EP

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