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Pichromene

CAT: 0804-HY-111209Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-111209Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pichromene (S14161) is an anticancer agent and weak PI3K inhibitor. Pichromene can effectively inhibit tumor growth in leukemia mouse models and can be used in cancer research[1][2].
CAS Number
883046-50-2
Product Name Alternative
S14161
UNSPSC
12352005
Hazard Statement
H315
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pichromene.html
Purity
98.7
Solubility
10 mM in DMSO
Smiles
O=[N+](C1=CC2=CC=CC(OCC)=C2OC1C3=CC=C(F)C=C3)[O-]
Molecular Formula
C17H14FNO4
Molecular Weight
315.30
Precautions
H315
References & Citations
[1]Mao X, et al. A small-molecule inhibitor of D-cyclin transactivation displays preclinical efficacy in myeloma and leukemia via phosphoinositide 3-kinase pathway. Blood. 2011 Feb 10;117 (6) :1986-97.|[2]Fouqué A, et al. A Novel Covalent mTOR Inhibitor, DHM25, Shows in Vivo Antitumor Activity against Triple-Negative Breast Cancer Cells. J Med Chem. 2015 Aug 27;58 (16) :6559-73.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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