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J1038

CAT: 0804-HY-111028Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-111028Size:1 Each
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Description
J1038 (T 5979345) is a selective HDAC8 inhibitor. J1038 binds the catalytic zinc ion of Schistosoma mansoni HDAC8 (smHDAC8) [1].
CAS Number
949727-86-0
Product Name Alternative
T 5979345
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/j1038.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(SC(C)C(N2)=O)C2=C1)NO
Molecular Formula
C10H10N2O3S
Molecular Weight
238.26
References & Citations
[1]Marek M, et al. Structural basis for the inhibition of histone deacetylase 8 (HDAC8), a key epigenetic player in the blood fluke Schistosoma mansoni. PLoS Pathog. 2013;9 (9) :e1003645.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
551004J1038

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