Displurigen

• UNSPSC Description:

  Displurigen (NSC375009) disrupts human embryonic stem cell pluripotency by targeting HSPA8. Displurigen inhibits ATPase activity of HSP70 (IC50 = 225 μM)[1].

• Target Antigen:

  HSP

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  others

• Assay Protocol:

  https://www.medchemexpress.com/displurigen.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC=CC(O)=C12)C=C(C3=CC=CC=C3)S2(=O)=O

• Molecular Weight:

  286.30

• References & Citations:

  [1]Yijie Geng, et al. A Chemical Biology Study of Human Pluripotent Stem Cells Unveils HSPA8 as a Key Regulator of Pluripotency. Stem Cell Reports. 2015 Dec 8;5(6):1143-1154.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  96156-26-2