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PU24FCl

CAT: 0804-HY-11039Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-11039Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PU24FCl is a specific inhibitor of Hsp90. PU24FCl exhibits wide-ranging anti-cancer activities. PU24FCl accumulates in tumors while being rapidly cleared from normal tissue[1].
CAS Number
422508-46-1
UNSPSC
12352005
Target
HSP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pu24fcl.html
Solubility
10 mM in DMSO
Smiles
FC1=NC2=C(N=C(CC3=CC(OC)=C(C(OC)=C3Cl)OC)N2CCCC#C)C(N)=N1
Molecular Formula
C20H21ClFN5O3
Molecular Weight
433.86
References & Citations
[1]Vilenchik M, et, al. Targeting wide-range oncogenic transformation via PU24FCl, a specific inhibitor of tumor Hsp90. Chem Biol. 2004 Jun;11 (6) :787-97.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HSP90

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