TTA-P1

• Description :

  TTA-P1 is a potent state-independent compound inhibiting human T-type calcium channel. T-type calcium channels play a role in diverse physiological responses including neuronal burst firing, hormone secretion, and cell growth. TTA-P1 has the potential for the research of absence epilepsy[1].

• UNSPSC :

  12352005

• Target :

  Calcium Channel

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/tta-p1.html

• Solubility :

  10 mM in DMSO

• Smiles :

  ClC1=CC(C(NC[C@H]2CCN(CCC(C)(C)C)C[C@H]2F)=O)=CC(Cl)=C1

• Molecular Formula :

  C19H27Cl2FN2O

• Molecular Weight :

  389.33

• References & Citations :

  [1]Uebele VN, Nuss CE, Fox SV, et al. Positive allosteric interaction of structurally diverse T-type calcium channel antagonists. Cell Biochem Biophys. 2009;55 (2) :81-93.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  T-type calcium channel

• CAS Number :

  [918333-06-9]