Products for Research Use Only
RegisterLogin

Mesdopetam

CAT: 0804-HY-109150Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-109150Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Mesdopetam (IRL790) is a dopamine D3 receptor antagonist (Ki=90 nM; IC50=9.8 μM for human recombinant D3 receptor) with psychomotor stabilizing properties. Mesdopetam is used for the research of motor and psychiatric complications in Parkinson disease[1][2].
CAS Number
1403894-72-3
Product Name Alternative
IRL790
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mesdopetam.html
Solubility
10 mM in DMSO
Smiles
CCCNCCOC1=CC(S(=O)(C)=O)=CC(F)=C1
Molecular Formula
C12H18FNO3S
Molecular Weight
275.34
References & Citations
[1]Waters S, et al. Preclinical Pharmacology of [2- (3-Fluoro-5-Methanesulfonyl-phenoxy) Ethyl] (Propyl) amine (IRL790), a Novel Dopamine Transmission Modulator for the Treatment of Motor and Psychiatric Complications in Parkinson Disease. J Pharmacol Exp Ther. 2020;374 (1) :113-125. |[2]Becanovic K, et al. Effects of a Novel Psychomotor Stabilizer, IRL790, on Biochemical Measures of Synaptic Markers and Neurotransmission. J Pharmacol Exp Ther. 2020;374 (1) :126-133.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
D3 Receptor

Alternative Products

CatalogName
MBS5799409Mesdopetam
M28670-01Mesdopetam hemitartrate

Popular Products