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Tenecteplase

CAT: 0804-HY-108845Size: 100 µgDry Ice: YesHazardous: No
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CAT#:0804-HY-108845Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tenecteplase (TNK-tPA) is a modified tissue plasminogen activator. Tenecteplase is a recombinant human tissue plasminogen activator (rt-PA) that has been bioengineered to produce mutations in three gene loci. Tenecteplase (TNK-tPA) can be used in the study of acute ischemic stroke[1][2].
CAS Number
191588-94-0
Product Name Alternative
TNK-tPA
UNSPSC
12352204
Target
Ser/Thr Protease
Type
Enzyme
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/tenecteplase.html
Purity
95.00
Solubility
10 mM in DMSO
Smiles
[Tenecteplase]
References & Citations
[1]Kvistad CE, et al. Tenecteplase versus alteplase for the management of acute ischaemic stroke in Norway (NOR-TEST 2, part A) : a phase 3, randomised, open-label, blinded endpoint, non-inferiority trial. Lancet Neurol. 2022 Jun;21 (6) :511-519.|[2]Thelengana A, et al. Tenecteplase versus alteplase in acute ischemic stroke: systematic review and meta-analysis[J]. Acta Neurologica Belgica, 2019, 119: 359-367.|[3]Correa-Paz C, et al., Pharmacological preclinical comparison of tenecteplase and alteplase for the treatment of acute stroke. J Cereb Blood Flow Metab. 2024 Aug;44 (8) :1306-1318.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Enzyme
Clinical Information
Launched

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