Enterodiol

• Description :

  Enterodiol is transformed by human intestinal bacteria from lignans contained in various whole-grain cereals, nuts, legumes, flaxseed, and vegetables. Enterodiol has an apoptotic effect in colorectal cancer (CRC) cells. Anti-cancer activities[1][2].

• CAS Number :

  [80226-00-2]

• UNSPSC :

  12352005

• Hazard Statement :

  H315-H319-H335

• Target :

  Apoptosis; Endogenous Metabolite

• Type :

  Reference compound

• Related Pathways :

  Apoptosis; Metabolic Enzyme/Protease

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/Enterodiol.html

• Solubility :

  10 mM in DMSO

• Smiles :

  OC[C@H](CC1=CC=CC(O)=C1)[C@@H](CC2=CC=CC(O)=C2)CO

• Molecular Formula :

  C18H22O4

• Molecular Weight :

  302.36

• Precautions :

  P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

• References & Citations :

  [1]Shin MK, et al. Apoptotic effect of enterodiol, the final metabolite of edible lignans, in colorectal cancer cells. J Sci Food Agric. 2019;99 (5) :2411-2419.|[2]Liu H, et al. Enterolactone has stronger effects than enterodiol on ovarian cancer. J Ovarian Res. 2017;10 (1) :49. Published 2017 Jul 24.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Human Endogenous Metabolite