Psora-4

• Description :

  Psora-4 is a potent and selective inhibitor of Kv1.3 (voltage-gated potassium channels) with an EC50 of 3 nM[1]. Psora-4 has immunosuppressive activity and inhibits proliferation of human and rat myelin-specific effector memory T cells in vitro[2].

• Product Name Alternative :

  5- (4-Phenylbutoxy) psoralen

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319, H335, H413

• Target :

  Potassium Channel

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/psora-4.html

• Purity :

  99.7

• Solubility :

  DMSO : 10 mg/mL (ultrasonic)

• Smiles :

  O=C1C=CC2=C(OCCCCC3=CC=CC=C3)C4=C(OC=C4)C=C2O1

• Molecular Formula :

  C21H18O4

• Molecular Weight :

  334.37

• Precautions :

  H315, H319, H335, H413

• References & Citations :

  [1]Vennekamp J, et al. Kv1.3-blocking 5-phenylalkoxypsoralens: a new class of immunomodulators. Mol Pharmacol. 2004 Jun;65 (6) :1364-74.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [724709-68-6]