RegisterLogin

RuBi-4AP

CAT: 0804-HY-108578Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-108578Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
RuBi-4AP, a derivative of 4-aminopyridine (4AP; HY-B0604), is a caged Kv channel blocker. RuBi-4AP contains a photolabile protecting group, allowing its effect to be controlled precisely in both space and time with light. RuBi-4AP can be used for the research of neuronal excitability, synaptic transmission, and signal propagation[1][2].
CAS Number
[851956-02-0]
UNSPSC
12352211
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rubi-4ap.html
Solubility
10 mM in DMSO
Smiles
NC1=CC=[N]([Ru+2]23([N]4=CC=CC=C4C5=CC=CC=[N]35)([N]6=CC=C(N)C=C6)[N]7=CC=CC=C7C8=CC=CC=[N]28)C=C1.[Cl-].[Cl-]
Molecular Formula
C30H28Cl2N8Ru
Molecular Weight
672.57
References & Citations
[1]Zayat L, et al. A new strategy for neurochemical photodelivery: metal-ligand heterolytic cleavage. J Am Chem Soc. 2003 Jan 29;125 (4) :882-3.|[2]Rowan MJ, et al. Distinct Kv channel subtypes contribute to differences in spike signaling properties in the axon initial segment and presynaptic boutons of cerebellar interneurons. J Neurosci. 2014 May 7;34 (19) :6611-23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-103527RuBi-GABA
HY-131885-01RuBi-Glutamate (hexafluorophosphate sodium)
HY-D1708RuBP-4S

Alternative Products

CatalogName
MBS5757740RuBi-4AP
MBS5757745RuBi-Nicotine
sc-472894RuBi-Dopa
B5454-10RuBi-Glutamate
T23277RuBi-GABA
T23276RuBi GABA trimethylphosphine
C02501Rubi Fructus Extract
464880-01RuBi-5-HT
MBS1038805-01Recombinant Zea mays Superoxide dismutase [Cu-Zn] 4AP (SODCC.2)
217760RuBi-Nicotine (Nicotinic Cholinergic Receptor Agonist, RuBi-Nicotine, nAChR Receptor Agonist, RuBi-Nicotine, Bis (2,2'-bipyridine-N, N') bis (S-nicotine-N1) Ruthenium (2+) Dichloride Complex Bis (2,2′-bipyridine-N, N′) bis (S-nicotine-N1) Ruthenium (2+) Dichloride Complex) discontinued

Popular Products