L-670596
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No


L-670596
Description :
L-670596 is an orally active and selective thrombsxane A2 receptor/prostaglandin receptor antagonist. L-670596 inhibits arachidonic acid (HY-109590) and U-44069 induced bronchoconstriction in the guinea pig. L-670596 also inhibits the aggregation of human platelet rich plasma induced by U-44069[1][2].UNSPSC :
12352005Target :
Prostaglandin ReceptorType :
Reference compoundRelated Pathways :
GPCR/G ProteinApplications :
Neuroscience-NeuromodulationField of Research :
OthersAssay Protocol :
https://www.medchemexpress.com/l-670596.htmlSolubility :
10 mM in DMSOSmiles :
O=C(O)CC1C(N(CC2=CC=C(S(=O)(C)=O)C=C2)C3=C4C=C(F)C=C3F)=C4CCC1Molecular Formula :
C22H21F2NO4SMolecular Weight :
433.47References & Citations :
[1]Ford-Hutchinson AW, et al. The pharmacology of L-670,596, a potent and selective thromboxane/prostaglandin endoperoxide receptor antagonist. Can J Physiol Pharmacol. 1989 Sep;67 (9) :989-93.|[2]Nuttall GA, et al. Protamine-heparin-induced pulmonary hypertension in pigs: effects of treatment with a thromboxane receptor antagonist on hemodynamics and coagulation. Anesthesiology. 1991 Jan;74 (1) :138-45.Shipping Conditions :
Room temperatureScientific Category :
Reference compound1Clinical Information :
No Development ReportedCAS Number :
[121083-05-4]

