(1R,1'S,3'R/1R,1'R,3'S)-L-054,264
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804-HY-108501
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

(1R,1'S,3'R/1R,1'R,3'S)-L-054,264
- CAS Number: 208706-12-1
- UNSPSC Description: (1R,1'S,3'R/1R,1'R,3'S)-L-054,264 is a selective non-peptide human somatostatin receptor subtype 2 (sst2) agonist. (1R,1'S,3'R/1R,1'R,3'S)-L-054,264 can be used in the study of retinal neuromodulation[1][2].
- Target Antigen: Somatostatin Receptor
- Type: Reference compound
- Related Pathways: GPCR/G Protein;Neuronal Signaling
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/1r-1-s-3-r-1r-1-r-3-s-l-054-264.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(N1CCC2(CC1)C=CC3=C2C=CC=C3)N[C@H](CC4=CNC5=C4C=CC=C5)C(NCC6CC(CN)CCC6)=O
- Molecular Weight: 539.71
- References & Citations: [1]Yang L, et al. Spiro[1H-indene-1,4'-piperidine] derivatives as potent and selective non-peptide human somatostatin receptor subtype 2 (sst2) agonists. J Med Chem. 1998 Jun 18;41(13):2175-9.|[2]Weir K, et al. A potential role for somatostatin signaling in regulating retinal neurogenesis. Sci Rep. 2021 May 26;11(1):10962. doi: 10.1038/s41598-021-90554-3. Erratum in: Sci Rep. 2021 Aug 16;11(1):16948.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported