Rezafungin

• Description :

  Rezafungin (Biafungin) is a next-generation, broad-spectrum, and long-lasting echinocandin. Rezafungin shows potent antifungal activity against Candida spp., Aspergillus spp., and Pneumocystis spp.[1][2].

• Product Name Alternative :

  Biafungin; CD101; SP-3025

• UNSPSC :

  12352005

• Target :

  Fungal

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/rezafungin.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1N2[C@]([C@@H](O)[C@@H](C)C2)([H])C(N[C@]([C@@H](C[C@@H](C(N[C@]([C@H](O)C)([H])C(N3[C@](C[C@@H](O)C3)([H])C(N[C@]([C@H](O)[C@H](C4=CC=C(O)C=C4)O)([H])C(N[C@@]1([H])[C@H](O)C)=O)=O)=O)=O)NC(C5=CC=C(C6=CC=C(C7=CC=C(OCCCCC)C=C7)C=C6)C=C5)=O)O)([H])OCC[N+](C)(C)C)=O

• Molecular Formula :

  C63H85N8O17

• Molecular Weight :

  1226.39

• References & Citations :

  [1]Sofjan AK, et al. Rezafungin (CD101), a next-generation echinocandin: A systematic literature review and assessment of possible place in therapy. J Glob Antimicrob Resist. 2018 Sep;14:58-64.|[2]Melanie Cushion, et al. Rezafungin Prophylactic Efficacy in a Mouse Model of Pneumocystis Pneumonia. VOLUME 25, ISSUE 3, SUPPLEMENT, S366, MARCH 01, 2019.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• Citation 01 :

  Antimicrob Agents Chemother. 2025 Aug 6;69 (8) :e0024125.|Preprints. 2023 May 17.|J Fungi (Basel) . 2024 May 31;10 (6) :397.

• CAS Number :

  [1396640-59-7]