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BIBP3226

CAT: 0804-HY-107726ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-107726ASize:1 Each
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Description
BIBP3226 is a potent and selective neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist, with Kis of 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF, respectively. BIBP3226 displays anxiogenic-like effect[1][2].
CAS Number
159013-54-4
UNSPSC
12352005
Target
Neuropeptide Y Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bibp3226.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](CCC/N=C(N)\N)NC(C(C1=CC=CC=C1)C2=CC=CC=C2)=O)NCC3=CC=C(C=C3)O
Molecular Formula
C27H31N5O3
Molecular Weight
473.57
References & Citations
[1]Mollereau C, et al. Agonist and antagonist activities on human NPFF (2) receptors of the NPY ligands GR231118 and BIBP3226. Br J Pharmacol. 2001 May;133 (1) :1-4.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NPY Y1 receptor

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