(S) -3,4-DCPG

• Description:

  (S) -3,4-DCPG is a selective agonist of metabotropic glutamate receptor 8a (mGluR8a) with an EC50 of 31 nM in AV12-664 cells expressing human mGluR8[1].

• Product Name Alternative:

  (S) -3,4-Dicarboxyphenylglycine

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H312, H332

• Target:

  MGluR

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/s-3-4-dcpg.html

• Purity:

  99.9

• Solubility:

  DMSO : 20 mg/mL (ultrasonic; warming)

• Smiles:

  OC(C1=C(C=CC([C@H](N)C(O)=O)=C1)C(O)=O)=O

• Molecular Formula:

  C10H9NO6

• Molecular Weight:

  239.18

• Precautions:

  H302, H312, H332

• References & Citations:

  [1]Thomas NK, et al. (S) -3,4-DCPG, a potent and selective mGlu8a receptor agonist, activates metabotropic glutamate receptors on primary afferent terminals in the neonatal rat spinal cord. Neuropharmacology. 2001 Mar;40 (3) :311-8.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  MGluR8

• CAS Number:

  201730-11-2