Hyzetimibe

CAT: 0804-HY-107176ASize: 1 EachDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-107176ASize:1 Each

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

Hyzetimibe is a cholesterol absorption inhibitor. Hyzetimibe blocks the intestinal absorption of cholesterol and phytol. Hyzetimibe is well tolerated in animal models, with an LDmax 2000 mg/kg in rats and an LDmax 500 mg/kg in rhesus monkeys[1].

CAS Number

1266548-74-6

Product Name Alternative

HS-25

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/hyzetimibe.html

Solubility

10 mM in DMSO

Smiles

OC/C(C1=CC=C(C=C1)F)=C\C[C@@H]2[C@](C3=CC=C(C=C3)O)([H])N(C4=CC=C(C=C4)F)C2=O

Molecular Formula

C25H21F2NO3

Molecular Weight

421.44

References & Citations

[1]Ruan Z, et al. Pharmacokinetics, pharmacodynamics, safety, and tolerability of hyzetimibe (HS-25) in healthy Chinese subjects. J Clin Pharmacol. 2014 Oct;54 (10) :1144-52.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 3

Alternative Products

Catalog	Name
T27565-01	Hyzetimibe

Hyzetimibe

Alternative Products

Popular Products