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Litoxetine

CAT: 0804-HY-106807-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-106807-01Size:1 mg
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Description
Litoxetine (SL 81.0385) is a selective 5-HT uptake inhibitor. Litoxetine is a 5-HT3 receptor antagonist with a Ki of 85 nM for cerebral 5-HT3 receptors. Litoxetine is an antidepressant and has antiemetic properties[1].
CAS Number
86811-09-8
Product Name Alternative
SL 81.0385
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/litoxetine.html
Solubility
10 mM in DMSO
Smiles
C1(COC2CCNCC2)=CC3=C(C=CC=C3)C=C1
Molecular Formula
C16H19NO
Molecular Weight
241.33
References & Citations
[1]I Angel, et al. Litoxetine: a selective 5-HT uptake inhibitor with concomitant 5-HT3 receptor antagonist and antiemetic properties. Eur J Pharmacol. 1993 Mar 2;232 (2-3) :139-45.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3

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