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Ceftobiprole medocaril

CAT: 0804-HY-106574Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-106574Size:1 Each
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Description
Ceftobiprole medocaril (BAL5788) is the parenteral proagent of Ceftobiprole. Ceftobiprole is a parenteral pyrrolidinone cephalosporin. Ceftobiprole is a broad-spectrum cephalosporin with high levels of in vitro activity against methicillin- (MRSA) and vancomycin-resistant staphylococci (VRSA) and penicillin-resistant streptococci. Ceftobiprole also inhibits gram-positive and gram-negative pathogens[1][2].
CAS Number
376653-43-9
Product Name Alternative
BAL5788
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ceftobiprole-medocaril.html
Solubility
10 mM in DMSO
Smiles
OC(C(N(C1=O)[C@@](SC2)([H])[C@@H]1NC(/C(C3=NSC(N)=N3)=N\O)=O)=C2/C=C(CCN4[C@@](CC5)([H])CN5C(OCC(OC6=O)=C(O6)C)=O)/C4=O)=O
Molecular Formula
C26H26N8O11S2
Molecular Weight
690.66
References & Citations
[1]W A Craig, et al. In vivo pharmacodynamics of ceftobiprole against multiple bacterial pathogens in murine thigh and lung infection models. Antimicrob Agents Chemother. 2008 Oct;52 (10) :3492-6.|[2]E Azoulay-Dupuis, et al. Efficacy of BAL5788, a prodrug of cephalosporin BAL9141, in a mouse model of acute pneumococcal pneumonia. Antimicrob Agents Chemother. 2004 Apr;48 (4) :1105-11.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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