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Trimazosin

CAT: 0804-HY-106554Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-106554Size:1 Each
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Description
Trimazosin is an orally active, quinazoline derivative which is structurally related to prazosin. Trimazosin shows hypotensive effect by selectively block α1-adrenoceptors[1][2].
CAS Number
35795-16-5
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/trimazosin.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCN(CC1)C2=NC3=C(C=C(C(OC)=C3OC)OC)C(N)=N2)OCC(C)(C)O
Molecular Formula
C20H29N5O6
Molecular Weight
435.47
References & Citations
[1]J Vincent, et al. The cardiovascular effects of trimazosin and prazosin in the rabbit. Clin Exp Pharmacol Physiol. 1986 Aug;13 (8) :593-608. |[2]H L Elliott, et al. Trimazosin in normotensive subjects. Clin Pharmacol Ther. 1984 Feb;35 (2) :156-60.|[3]J. P. Buyniski, et al. Effects of Tiodazosin, Prazosin, Trimazosin and Phentolamine on Blood Pressure, Heart Rate and on Pre- and Postsynaptic α-Adrenergic Receptors in the Rat. Clinical and Experimental Hypertension , 1980, Vol.2 (6), p.1039-1066.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
α adrenergic receptor

Alternative Products

CatalogName
T62476-01Trimazosin
sc-473810Trimazosin Hydrochloride
sc-475001Trimazosin-d8 Hydrochloride

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