Products for Research Use Only
RegisterLogin

Nipradolol

CAT: 0804-HY-106523Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-106523Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Nipradolol (KT-210; K-351) is a potent blocker of alpha-1-adrenergic receptors. Nipradolol inhibits the increase of intraocular pressure (IOP) in an albino rabbit model induced by Phenylephrine. Nipradolo suppresses the noradrenaline (NA) -induced muscles contraction, also exhibits vasodilator activity on the dog coronary artery[1][2].
CAS Number
81486-22-8
Product Name Alternative
KT 210; K 351; Hypadil
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/nipradolol.html
Solubility
10 mM in DMSO
Smiles
CC(C)NCC(O)COC1=C2C(CC(O[N+]([O-])=O)CO2)=CC=C1
Molecular Formula
C15H22N2O6
Molecular Weight
326.34
References & Citations
[1]3,4-dihydro-8- (2-hydroxy-3-isopropylaminopropoxy) -3-nitroxy-2H-1-benzopyran (K-351) and its denitrated derivative on smooth muscle cells of the dog coronary artery. Br J Pharmacol. 1983 May;79 (1) :285-95. |[2]Nishio K. Alpha-1-adrenoceptor blocking activity of KT-210 (nipradilol ophthalmic solution) on intraocular pressure in the rabbit eye[J]. Nihon Ganka Kiyo (Folia Ophthalmol Jpn), 1999, 50: 655-660.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
α adrenergic receptor

Alternative Products

CatalogName
TRC-N478950-100MGNipradolol
460781Nipradolol-d7

Popular Products