Sabcomeline

• Description :

  Sabcomeline (SB-202026) is a potent and functionally selective muscarinic M1 receptor partial agonist that improve cognition. Sabcomeline can be used for Alzheimer's disease research[1][2].

• Product Name Alternative :

  SB-202026; Memric

• UNSPSC :

  12352005

• Target :

  MAChR

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neurodegeneration

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/sabcomeline.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CO/N=C([C@@H]1C2CCN(CC2)C1)\C#N

• Molecular Formula :

  C10H15N3O

• Molecular Weight :

  193.25

• References & Citations :

  [1]Hosoi R, et al. Effect of sabcomeline on muscarinic and dopamine receptor binding in intact mouse brain. Ann Nucl Med. 2003;17 (2) :123-130. |[2]Hatcher JP, et al. Sabcomeline (SB-202026), a functionally selective M1 receptor partial agonist, reverses delay-induced deficits in the T-maze. Psychopharmacology (Berl) . 1998;138 (3-4) :275-282.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1

• Isoform :

  MAChR1

• CAS Number :

  [159912-53-5]