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Sabcomeline

CAT: 0804-HY-106432Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-106432Size:1 Each
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Description
Sabcomeline (SB-202026) is a potent and functionally selective muscarinic M1 receptor partial agonist that improve cognition. Sabcomeline can be used for Alzheimer's disease research[1][2].
CAS Number
159912-53-5
Product Name Alternative
SB-202026; Memric
UNSPSC
12352005
Target
MAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sabcomeline.html
Solubility
10 mM in DMSO
Smiles
CO/N=C([C@@H]1C2CCN(CC2)C1)\C#N
Molecular Formula
C10H15N3O
Molecular Weight
193.25
References & Citations
[1]Hosoi R, et al. Effect of sabcomeline on muscarinic and dopamine receptor binding in intact mouse brain. Ann Nucl Med. 2003;17 (2) :123-130. |[2]Hatcher JP, et al. Sabcomeline (SB-202026), a functionally selective M1 receptor partial agonist, reverses delay-induced deficits in the T-maze. Psychopharmacology (Berl) . 1998;138 (3-4) :275-282.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
MAChR1

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