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Atilmotin

CAT: 0804-HY-106258Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-106258Size:1 Each
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Description
OHM 11638 (Atilmotin), an analogue of the (1-14) fragment of porcine motilin, is a motilin receptor agonist with a pKd of 8.94 for the motilin receptor. OHM 11638 affects esophageal, lower esophageal sphincter (LES), and gastric motility. OHM 11638 increases LES and gastric pressures, OHM 11638 can be used as prokinetic agents[1][2].
CAS Number
533927-56-9
Product Name Alternative
OHM 11638; BAX-ACC 1638; MOT 288
UNSPSC
12352209
Target
Motilin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/atilmotin.html
Solubility
10 mM in DMSO
Smiles
C[N+](C)(C)[C@@H](CC1=CC=CC=C1)C(N[C@@H](C(C)C)C(N2[C@@H](CCC2)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(N[C@@H]([C@H](O)C)C(N[C@H](C(NCC(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(N[C@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCCCN)=O)=O)=O)=O)=O)=O)=O)CC3=CC=C(C=C3)O)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O
Molecular Formula
C86H135N20O19+
Molecular Weight
1753.11
References & Citations
[1]Peeters T L. Motilin and the Discovery and Development of Motilinomimetics. Old Herborn University Seminar Monograph. INSTITUTE FOR MICROBIOLOGY AND BIOCHEMISTRY, 1997, 9: 77-87.|[2]Korimilli A, Parkman HP. Effect of atilmotin, a motilin receptor agonist, on esophageal, lower esophageal sphincter, and gastric pressures. Dig Dis Sci. 2010 Feb;55 (2) :300-6.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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CatalogName
T30199Atilmotin

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