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Eniporide

CAT: 0804-HY-106150Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-106150Size:1 Each
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Description
Eniporide (EMD 96785) is a Na (+) /H (+) exchange (NHE) inhibitor. Eniporide specifically inhibits the NHE-1 isoform. Eniporide improves cardiac performance inhibition associated with myocardial ischemia/reperfusion in animals, and limits infarct size in experimental models. Eniporide regulates cardiac performance and high-energy phosphate content in clinically relevant pig models of CPB and cardiac arrest[1][2].
CAS Number
176644-21-6
Product Name Alternative
EMD-96785
UNSPSC
12352200
Hazard Statement
H302-H315-H319-H332-H335
Target
Na+/H+ Exchanger (NHE)
Type
Biochemical Assay Reagents
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/eniporide.html
Solubility
10 mM in DMSO
Smiles
CS(=O)(C1=C(N2C=CC=C2)C=C(C)C(C(NC(N)=N)=O)=C1)=O
Molecular Formula
C14H16N4O3S
Molecular Weight
320.37
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Zeymer U, et al. The Na (+) /H (+) exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction. Results of the evaluation of the safety and cardioprotective effects of eniporide in acute myocardial infarction (ESCAMI) trial. J Am Coll Cardiol. 2001 Nov 15;38 (6) :1644-50. |[2]Klass O, et al. Effect of the Na+/H+ exchange inhibitor eniporide on cardiac performance and myocardial high energy phosphates in pigs subjected to cardioplegic arrest. Ann Thorac Surg. 2004 Feb;77 (2) :658-63.
Shipping Conditions
Room temperature
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported

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C3709-10Eniporide
A14139-100ENIPORIDE 100mg
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A14139-5ENIPORIDE 5mg
A14139-200ENIPORIDE 200mg
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