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Mazaticol

CAT: 0804-HY-105793Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-105793Size:1 Each
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Description
Mazaticol is an anticholinergic agent. Mazaticol blocks the muscarinic acetylcholine receptors and cholinergic nerve activity. Mazaticol is a potent 3H-QNB and 3H-PZ binding inhibitor, can bind to the M2 receptors with high affinity. Mazaticol exhibits inhibitory effects on dopamine uptake in the striatal nerve terminal. Mazaticol can be used for parkinsonian syndrome research[1][2].
CAS Number
42024-98-6
UNSPSC
12352005
Target
MAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mazaticol.html
Solubility
10 mM in DMSO
Smiles
CC1(C)[C@H](N(C)[C@H](CC1)C2)C[C@@H]2OC(C(C3=CC=CS3)(C4=CC=CS4)O)=O
Molecular Formula
C21H27NO3S2
Molecular Weight
405.57
References & Citations
[1]Niimi Y, et al. Mazaticol for Treating Parkinson. 2020.|[2]Katayama S, et al. Effects of anticholinergic antiparkinsonian drugs on binding of muscarinic receptor subtypes in rat brain. Res Commun Chem Pathol Pharmacol. 1990;69 (3) :261-270.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAChR2

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