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Azidamfenicol

CAT: 0804-HY-105674Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-105674Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Azidamfenicol is a broad-spectrum chloramphenicol-like antibiotic. Azidamfenicol inhibits ribosomal peptidyltransferase (Ki=22 μM) [1]. Azidamfenicol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
CAS Number
13838-08-9
UNSPSC
12352005
Hazard Statement
H302
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/azidamfenicol.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@H](CO)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1)CN=[N+]=[N-]
Molecular Formula
C11H13N5O5
Molecular Weight
295.25
Precautions
P264-P270-P330-P501
References & Citations
[1]Bhuta P, et al. Analogues of chloramphenicol: circular dichroism spectra, inhibition of ribosomal peptidyltransferase, and possible mechanism of action. J Med Chem. 1980 Dec;23 (12) :1299-305.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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