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Nomegestrol

CAT: 0804-HY-105634Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-105634Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nomegestrol is a potent and orally available progestin, acts as a selective full progesterone receptor agonist, with a Kd of 5.44 nM for rat uterine progesterone receptor, and has moderate antiandrogenic activity and strong antiestrogenic activity.
CAS Number
58691-88-6
UNSPSC
12352211
Hazard Statement
H315-H319-H320
Target
Progesterone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology; Cancer
Assay Protocol
https://www.medchemexpress.com/Nomegestrol.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@](CC[C@]2(O)C(C)=O)([H])[C@@]3([H])[C@]([C@]4([H])C(C(C)=C3)=CC(CC4)=O)([H])CC1
Molecular Formula
C21H28O3
Molecular Weight
328.45
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Duc I, et al. Interaction of [3H]nomegestrol acetate with cytosolic progesterone receptors from the rat uterus. Steroids. 1991 Jun;56 (6) :325-8.|[2]Mueck AO, et al. Nomegestrol acetate, a novel progestogen for oral contraception. Steroids. 2011 May;76 (6) :531-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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