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Lexipafant

CAT: 0804-HY-105198-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-105198-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lexipafant is a platelet-activating factor (PAF) antagonist that inhibits the inflammatory response and is used in the research of acute pancreatitis.
CAS Number
139133-26-9
Product Name Alternative
BB-882
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Platelet-activating Factor Receptor (PAFR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/lexipafant.html
Solubility
10 mM in DMSO
Smiles
CC1=NC2=CN=CC=C2N1CC3=CC=C(C=C3)S(N(C)[C@@H](CC(C)C)C(OCC)=O)(=O)=O
Molecular Formula
C23H30N4O4S
Molecular Weight
458.57
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Kingsnorth AN, Galloway SW, Formela LJ. Randomized, double-blind phase II trial of Lexipafant, a platelet-activating factor antagonist, in human acute pancreatitis. Br J Surg. 1995;82 (10) :1414-1420. |[2]Galloway SW, Kingsnorth AN. Lung injury in the microembolic model of acute pancreatitis and amelioration by lexipafant (BB-882), a platelet-activating factor antagonist. Pancreas. 1996;13 (2) :140-146.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

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CatalogName
T27821-01Lexipafant

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