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Disomotide

CAT: 0804-HY-105039Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-105039Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Disomotide (G209-2M) is a melanoma antigen that enhances the generation of cytotoxic T lymphocytes (CTL) recognizing native G209 as well as melanoma[1][2].
CAS Number
181477-43-0
Product Name Alternative
G209-2M; GP100:209-217 (210M) ; MPS-22
UNSPSC
12352209
Target
Others
Type
Peptides
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/disomotide.html
Solubility
10 mM in DMSO
Smiles
O=C(N(CCC1)[C@@H]1C(N[C@H](C(N[C@@H](CO)C(N[C@H](C(O)=O)C(C)C)=O)=O)CC2=CC=CC=C2)=O)[C@H](C(C)C)NC([C@H](CCC(N)=O)NC([C@H](CC(O)=O)NC([C@H](CCSC)NC([C@@H](N)[C@@H](C)CC)=O)=O)=O)=O
Molecular Formula
C47H74N10O14S
Molecular Weight
1035.21
References & Citations
[1]Yang S, et al. Antimelanoma activity of CTL generated from peripheral blood mononuclear cells after stimulation with autologous dendritic cells pulsed with melanoma gp100 peptide G209-2M is correlated to TCR avidity. J Immunol. 2002 Jul 1;169 (1) :531-9.|[2]Ahmadzadeh M, et al. IL-2 and IL-15 each mediate de novo induction of FOXP3 expression in human tumor antigen-specific CD8 T cells. J Immunother. 2007 Apr;30 (3) :294-302.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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