ACDPP

• UNSPSC Description:

  ACDPP is a specific mGluR5 antagonist. ACDPP partially bolcks the increase of fragile X mental retardation protein (FMRP) caused by DHPG (HY-12598A) (group I mGluR Agonist)[1].

• Target Antigen:

  mGluR

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/acdpp.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=NC(Cl)=C(N(C)C)N=C1N)NC2=NC=CC=C2

• Molecular Weight:

  292.72

• References & Citations:

  [1]Wang H, et al. Roles of calcium-stimulated adenylyl cyclase and calmodulin-dependent protein kinase IV in the regulation of FMRP by group I metabotropic glutamate receptors. J Neurosci. 2008 Apr 23;28(17):4385-97.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  37804-11-8