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Org20599

CAT: 0804-HY-103498Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-103498Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Org20599 is a positive allosteric modulator and at higher concentrations direct agonist of GABAA receptor with an EC50 of 1.1 μM[1].
CAS Number
156685-94-8
UNSPSC
12352005
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/org20599.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@@H](C(CCl)=O)CC[C@@]1([H])[C@]3([H])CC[C@@]4([H])C[C@H](O)[C@@H](N5CCOCC5)C[C@]4(C)[C@@]3([H])CC2
Molecular Formula
C25H40ClNO3
Molecular Weight
438.04
References & Citations
[1]Visser SA, et al. Neuroactive steroids differ in potency but not in intrinsic efficacy at the GABA (A) receptor in vivo. J Pharmacol Exp Ther. 2002 Nov;303 (2) :616-26.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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