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BIBU1361

CAT: 0804-HY-103438Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-103438Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BIBU1361 induces apoptosis and inhibits autophagy. BIBU1361 inhibits pro-survival pathways Akt/mTOR and gp130/JAK/STAT3, and decreased levels of pro-inflammatory cytokine IL-6[1].
CAS Number
793726-84-8
UNSPSC
12352005
Target
Akt; Apoptosis; Autophagy
Type
Reference compound
Related Pathways
Apoptosis; Autophagy; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bibu1361.html
Solubility
10 mM in DMSO
Smiles
CCN(CC1CCN(C2=NC3=C(NC4=CC=C(F)C(Cl)=C4)N=CN=C3C=N2)CC1)CC
Molecular Formula
C22H27ClFN7
Molecular Weight
443.95
References & Citations
[1]Ruchi Ghildiyal, et, al. EGFR inhibitor BIBU induces apoptosis and defective autophagy in glioma cells. Mol Carcinog. 2013, 52,12.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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